Well. Great deal for whoever owned Mojang (I guess Notch got most of it) ... I knew what I'd do with that insanely ridiculous amount of money. I would never had thought that someone would pay so much for a studio ...
Minecraft 2 maybe would be an idea for Microsoft ... something that is a little more polished when it comes to chunk loading and rendering effects. Maybe speed up the official Modding API or scrap it, which would have extreme backslash though.
Anyway. Big things seemed to have happened with the "deceleration" that Bukkit was, and is owned by Mojang and now that Mojang is owned by Microsoft but we'll see what happens in the end.
I hope Microsoft doesn't get the idea that they could just step in and give orders in a gaming segment that is so new and different. They need to work together with the guys at Mojang who know Minecraft and its customers well. It is a chance for them but also a big responsibility.
I just don't see how they want to make that money back any time soon. Mojang itself was only really successful with Minecraft thus far.